Rachel moves in with Monica in season one after nearly marrying Barry Farber, an orthodontist who decides to go on his and Rachel's honeymoon with her maid of honor Mindy.

In the second episode of the series, Carol tells Ross that she is pregnant with his child and is having the baby with her partner Susan, though she wishes Ross to be part of the baby's life.

The most prominent fixture of Central Perk is the large orange couch that the characters usually sit on. It can seat four of the Friends at one time. One of the others then occupies the green chair on the right and, if all six are present, there is a table with one chair to the left that sits the last person.

Kathleen Turner plays Chandler's drag-queen father, Charles Bing, in several episodes, including "The One with Chandler's Dad".

The name Emma is a gift from Monica, who had previously been reserving the name for her own child.

In "The One With Frank Jr.", the gang discusses which five celebrities they would put on their "list" of people they're allowed to sleep with and their significant other can't get mad. Ross bumps Isabella Rossellini off the list because she is out of the country all the time, and he is unlikely to meet her. When he ends up running into Isabella at the coffee house, Rachel lets him hit on her anyway, which ends in comical rejection.

Joey has seven sisters: Mary Therese, Mary Angela, Dina, Gina, Tina, Veronica, and Cookie.

When the name is discovered during one episode of the show, Chandler explains that "Muriel" is a family name.

In "The One Where Everybody Finds Out", Joey accidentally mentions Huggsy, who he describes as his "bedtime penguin pal"

In "The One Where The Stripper Cries", Chandler and Ross try to impress Missy Goldberg, a girl they both have a crush on, by telling her that their band, "Way, No Way", is going to be playing the Asian Student Union.