Sheldon J. Plankton despises Mr. Krabs for running a successful restaurant because his own business rarely gets any customers.

In the ending of many Looney Tunes cartoons, Porky Pig bursts through a bass drum and stutters his signature line: "Th-Th-The, Th-Th-The, Th-Th ... That's all, folks!"

Exiled from his home planet Zetox for inventing a weapon capable of destroying the universe, Gazoo's punishment was to serve prehistoric "dumb-dumbs" Fred and Barney. Invisible to other adults, Gazoo provided questionable advice to his two charges and occasionally reported to his leader, the Great Gazam. The character was somewhat controversial among diehard Flintstones fans as he added a futuristic element to the otherwise prehistoric cartoon.

Although Yu-Gi-Oh first appeared in comic form in 1996, it was two years later, in 1998, that it really became a huge hit with the release of a 27-episode television series and a collectible card game. Kids began collecting cards and monsters so that they could duel like their favorite Yu-Gi-Oh characters and the phenomenon quickly spread to other countries, including the United States, where some duelists paid thousands of dollars for a single Yu-Gi-Oh card on auction sites such as eBay.

Although Walt Disney wanted The Beatles to voice the vultures, John Lennon nixed the idea. However, the vultures were still created in The Beatles' image.

Stewie, equipped with his teddy bear Rupert and his laser gun, has, on several occasions, almost single handedly taken over the world.

Created by Otto Messmer for the Pat Sullivan Studio, Felix was a smash hit with audiences and held the title of world's most popular cartoon character for a few years until Walt Disney introduced the world to a certain mouse. Unfortunately for Felix, the Pat Sullivan Studio was behind the curve in adding sound to their cartoons, and lost much of the market to other, more technologically advanced studios like Fleischer and Disney.

Canadian voice actor Peter Cullen voiced both Eeyore and Optimus Prime.

Kenny died in nearly every episode before returning in the next with little-to-no explanation.

The seventh son of a seventh son, Jonny's best friend and adoptive brother Hadji seems to possess mystical powers (including snake-charming, levitation and hypnotism), which may or may not be attributed to parlor trickery.