Jebediah Springfield founded Springfield in 1796 while looking for "New Sodom" with his partner Shelbyville Manhattan. Springfield & Manhattan went their separate ways & Manhattan went on to found the rival town of Shelbyville.
Almost every episode of The Simpsons shows the Simpson family doing something different as they sit on the couch to watch t.v. In some of the opening credits, Bart also writes something different on the blackboard & Lisa sometimes plays a different solo on her saxophone. The couch segment is often the only one of the three gags to survive editing to shorten the opening.
Ned owns The Leftorium, which specializes in products for left-handed people. This is a benefit to the surprisingly large proportion of Springfield's left-handed citizens, including Bart Simpson, Principal Skinner, Mr. Burns, and Moe Szyslak.